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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By Abby Olena | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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Single-cell analyses from mouse samples detail the changes in cell distribution during infections.

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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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image: Live Cell Extractions

Live Cell Extractions

By Ruth Williams | October 1, 2017

Nanostraws that collect specimens from cells without killing them allow for repeated sampling.

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image: Sex Reversal Mystery Explained?

Sex Reversal Mystery Explained?

By Jef Akst | June 15, 2017

A proposed mechanism for how bearded dragons with male chromosomes hatch as females at high temperatures

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Adding RNA sequencing analysis to genomic sequencing helps scientists uncover mutations likely responsible for genetic disorders they might otherwise miss.

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image: Massively Parallel Perturbations

Massively Parallel Perturbations

By Ruth Williams | March 1, 2017

Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.

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image: Infographic: Single-Cell CRISPR Screens

Infographic: Single-Cell CRISPR Screens

By Ruth Williams | March 1, 2017

See how two new methods track responses to unique genetic manipulations in numerous individual cells in parallel.

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Researchers solve the mystery of 15-year-old mutant ferns with disrupted sex determination.

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image: Noncoding RNAs Not So Noncoding

Noncoding RNAs Not So Noncoding

By Ruth Williams | June 1, 2016

Bits of the transcriptome once believed to function as RNA molecules are in fact translated into small proteins.

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