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tag induced pluripotent stem cell disease medicine immunology neuroscience microbiology

Artist’s rendition of a neuron silhouetted against a glowing red background.
SNO-y Protein Levels Help Explain Why More Women Develop Alzheimer’s
Dan Robitzski | Jan 6, 2023 | 4 min read
Female postmortem brains contain more S-nitrosylated C3 proteins, likely linked to menopause, which instruct immune cells to kill neuronal synapses.
Human Pluripotent Cells Pass Safety Test
Douglas Steinberg | Sep 1, 2002 | 7 min read
Image: ©2001 MacMillan Publishers Ltd.  PLURIPOTENT-CELL PIPELINE: To obtain embryonic germ cells, researchers culture primordial germ cells (PGCs) dissected from the genital ridge. If left in situ, a PGC develops into spermatozoa or ova after its imprints have been erased and reestablished. Embryonic stem cells come from the blastocyst's inner cell mass. (Reprinted with permission, Nature 414:122-8, 2001) Because the science is hard and the politics mean, progress in understanding
Illustration showing the upper part of a human body connected to a DNA helix
Unraveling the Mystery of Zombie Genes
Iris Kulbatski, PhD | Oct 31, 2023 | 6 min read
Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications. 
Stem Cells Tapped to Replenish Organs
Douglas Steinberg | Nov 26, 2000 | 10+ min read
Credit: Eric LaywellAn astrocyte monolayer that can be coaxed into becoming multipotent neural stemlike cells Editors Note: This is the second of two articles on issues raised by recent stem cell discoveries. The first article appeared in the November 13 issue "All politics is local" was a famous maxim of Thomas "Tip" O'Neill, the late speaker of the House of Representatives, and the same can be said of medically useful stem cells. Progenitor cells may prove to be more or less pluripotent in th
Dopamine Neuron Implants Ease Parkinsonā€™s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018 | 3 min read
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
A Paradigm Shift in Stem Cell Research?
Ricki Lewis | Mar 5, 2000 | 9 min read
Photo: E.D. Laywell, UT MemphisMultipotent clones of cells derived from the adult human brain With the promises and challenges of stem cell research in the headlines, visions of artificial livers dance in the public's eye. Bioethicists, politicians, and citizens alike continue to debate whether public funds should be used to obtain cells from human embryos and fetuses. On the scientific front, however, the implications of stem cell research are even more profound than offering replacement parts.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Natural Killer Cell Therapies Catch Up to CAR T
Bianca Nogrady | Apr 1, 2020 | 8 min read
There’s a new cell-based cancer immunotherapy on the block.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.

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