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The structure of a biological cell (macro)
The Long and Winding Road to Eukaryotic Cells
Amanda Heidt | Oct 17, 2022 | 10+ min read
Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat
Illuminating Behaviors
Douglas Steinberg | Jun 1, 2003 | 6 min read
Courtesy of Genevieve Anderson If not for Nobel laureates Thomas Hunt Morgan, Eric R. Kandel, and Sydney Brenner, the notion of a general behavioral model might seem odd. Behaviors, after all, are determined by an animal's evolutionary history and ecological niche. They are often idiosyncratic, shared in detail only by closely related species. But, thanks to Morgan's research in the early 20th century, and Kandel's and Brenner's work over the past 35 years, the fly Drosophila melanogaster, t
Elemental Shortage
Brendan Borrell | Nov 1, 2010 | 10+ min read
By Brendan Borrell ELEMENTAL SHORTAGE The world is running out of cheap phosphorus, the element that lies at the heart of great agricultural advances and thorny environmental problems. Biologists are only now beginning to understand what it means for evolution and human health. James Elser at a study site in southern Norway Although a limnologist in Phoenix and a molecular biologist in Atlanta have never met before, a single element ties them together.
The Prescient Placenta
Christopher Coe | Aug 1, 2015 | 10 min read
The maternal-fetal interface plays important roles in the health of both mother and baby, even after birth.
Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
Notebook
The Scientist Staff | Mar 1, 1998 | 7 min read
NICOTINE FOE: Richard Johnson, right, professor and director of neurology at Johns Hopkins University Medical School, welcomes former Surgeon General C. Everett Koop to the podium for his talk on the tobacco agreements. While President Bill Clinton praised research and denounced tobacco in one breath during his February 13 speech at the American Association for the Advancement of Science (AAAS) annual meeting, his exhalations failed to mention that his plans for stoking one depend on snuffing

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