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Surpassing the Law of Averages
Jeffrey M. Perkel | Sep 1, 2009 | 7 min read
By Jeffrey M. Perkel Surpassing the Law of Averages How to expose the behaviors of genes, RNA, proteins, and metabolites in single cells. By necessity or convenience, almost everything we know about biochemistry and molecular biology derives from bulk behavior: From gene regulation to Michaelis-Menten kinetics, we understand biology in terms of what the “average” cell in a population does. But, as Jonathan Weissman of the University of Califo
The Genetics of Society
Claire Asher and Seirian Sumner | Jan 1, 2015 | 10 min read
Researchers aim to unravel the molecular mechanisms by which a single genotype gives rise to diverse castes in eusocial organisms.
Elemental Shortage
Brendan Borrell | Nov 1, 2010 | 10+ min read
By Brendan Borrell ELEMENTAL SHORTAGE The world is running out of cheap phosphorus, the element that lies at the heart of great agricultural advances and thorny environmental problems. Biologists are only now beginning to understand what it means for evolution and human health. James Elser at a study site in southern Norway Although a limnologist in Phoenix and a molecular biologist in Atlanta have never met before, a single element ties them together.
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The Scientist Staff | Sep 27, 1992 | 3 min read
The University of Cincinnati Medical Center has established a $6.5 million Center for Environmental Genetics and has named Daniel W. Nebert, a professor of environmental health, to be its first director. Nebert says the center is the first of its kind in the world to study the genetic link between environmental contaminants and human health. The center opened at the University of Cincinnati in mid-August in conjunction with the National Institutes of Health's National Institute of Environmental
Building a Better Biosensor
Mike May | May 23, 2004 | 8 min read
A GRADIENT OF PORE SIZES:Courtesy of Michael J. Sailorimparts a rainbow of colors to a porous silicon chip, one of a variety of new biosensor technologies in development around the world. The different colors correspond to different sized pores, ranging from a few nanometers to hundreds of nanometers in diameter. These pores help the device discriminate and detect proteins and other molecules based on their size.One morning in March 1995, the deadly nerve gas sarin wafted through the Tokyo subwa
Genetic Parasites and a Whole Lot More
Barry Palevitz | Oct 15, 2000 | 10+ min read
Photo: Ori Fragman, Hebrew University Hordeum spontaneum, the plant studied for BARE-1 retroelements. With genome sequences arriving almost as regularly as the morning paper, the public's attention is focused on genes--new genes to protect crops against pests; rogue genes that make bacteria resistant to antibiotics; faulty genes that, if fixed, could cure diseases such as muscular dystrophy. What many people don't realize is that genes account for only part of an organism's DNA, and in many c
Epigenetics: Genome, Meet Your Environment
Leslie Pray | Jul 4, 2004 | 10+ min read
©Mehau Kulyk/Photo Researchers, IncToward the end of World War II, a German-imposed food embargo in western Holland – a densely populated area already suffering from scarce food supplies, ruined agricultural lands, and the onset of an unusually harsh winter – led to the death by starvation of some 30,000 people. Detailed birth records collected during that so-called Dutch Hunger Winter have provided scientists with useful data for analyzing the long-term health effects of prenat

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