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Technology

Microarray Data Stands Up to Scrutiny
Lissa Harris(lharris@the-scientist.com) | Jul 17, 2005 | 6 min read
The power and promise of microarrays are vast.
Automated Colony Pickers Evolve
Helen Dell(hdell@the-scientist.com) | Jul 3, 2005 | 6 min read
Everyone knows that the first genome sequencing projects took years of work and represent the combined product of tens of thousands of individual fragments.
Fish Eggs Spawn a DNA Delivery Revolution
Laura Lane(llane@the-scientist.com) | Jul 3, 2005 | 6 min read
Atlantic salmon seems an unlikely source of inspiration for a research gadget.
You Need It, They Build It
Jeff Minerd(jminerd@the-scientist.com) | Jul 3, 2005 | 7 min read
David Profitt was a little confused when a developmental biologist walked into his engineering shop and asked if Profitt could make an automated embryo sorter using a Fax machine.
Biology by the Numbers
Jeffrey Perkel(jperkel@the-scientist.com) | Jun 19, 2005 | 6 min read
When the graduate students and postdocs in Martin Wilson's lab at the University of California, Davis, need to do image processing, they look to an unlikely source.
New Thermocyclers Hit the Street
Leslie Pray(lpray@the-scientist.com) | Jun 5, 2005 | 6 min read
In less than three decades, the polymerase chain reaction has evolved from a slow, labor-intensive practice that was initially performed manually and only by the initiated few, to a fast, powerful, easy-to-use tool found in life science laboratories everywhere.
Finding Heterogeneous Loci with Human-Mouse Cell Hybrids
Josh Roberts | Jun 5, 2005 | 3 min read
Bert Vogelstein has an unusual complaint about the humans whose genetic defects he studies: "We're diploid."
Microfluidics Meets its Market
Megan Stephan(mstephan@the-scientist.com) | May 22, 2005 | 6 min read
It's been a busy year for the microfluidics industry.
Machining the Body
Aileen Constans(aconstans@the-scientist.com) | May 8, 2005 | 9 min read
Two years ago, cell biologist Vladimir Mironov of the Medical University of South Carolina, Charleston, created a buzz in the tissue-engineering world by predicting that in the not-so-distant future, scientists would be able to print whole replacement organs, and eventually whole bodies, using machines similar to desktop printers.
Kinase Screening Services Probe Signaling Pathways
Lissa Harris(lharris@the-scientist.com) | May 8, 2005 | 6 min read
Kinases, the enzymes that catalyze phosphorylation events, have been implicated in hundreds of different diseases, including cancer, inflammatory diseases, and neurological disorders.
Quantum Dots Get Smaller
Karen Heyman(kheyman@the-scientist.com) | May 8, 2005 | 6 min read
For all the hype about nanotechnology, sometimes small isn't quite small enough.
Growing Pains for Metabolomics
Bennett Daviss(bdaviss@the-scientist.com) | Apr 24, 2005 | 8 min read
Co. withdrew the painkiller Vioxx from the market last September after the drug was linked to increased risks of heart attack and stroke, more than one metabolomics researcher shook their heads and thought, "If only ...."
Making the Most of Fluorescence
Linda Sage(lsage@the-scientist.com) | Apr 24, 2005 | 7 min read
Fluorescence microscopy is ubiquitous these days.
The Million-Dollar Mislabel
Alison McCook(amccook@the-scientist.com) | Apr 10, 2005 | 8 min read
In June 2003, the US Environmental Protection Agency surprised Plymouth State University in New Hampshire with a routine inspection of how their labs were managing chemical waste.
Gene Finding with Hidden Markov Models
Karen Heyman(kheyman@the-scientist.com) | Mar 27, 2005 | 8 min read
made history in 1995 when it became the first free-living organism to have its genome completely sequenced.
Glycomics Researchers Search for the Elusive Sweet Spot
Charles Choi(cchoi@the-scientist.com) | Mar 27, 2005 | 6 min read
Cells are coated with carbohydrates, as are many of the proteins and lipids contained within cells.
Squeeze More from Your Samples
Aileen Constans(aconstans@the-scientist.com) | Mar 27, 2005 | 6 min read
In the mid-1990s, toxicologist Raymond Biagini was looking for a faster way to evaluate pest-control workers for exposure to pesticides.
Keeping Tabs on Cultured Cells
Lissa Harris(lharris@the-scientist.com) | Mar 13, 2005 | 6 min read
THE CULTURE WITHIN:Photo courtesy of Drs. C.C. Uphoff and H.G. Drexler, DSMZ-German Collection of Microorganism and Cell Cultures, Braunschweig, GermanyHeLa cell line infected with Mycoplasma hyorhinis. Scanning electron micrograph of critical point-dried cell culture grown on cover slips. Note the loop- and rod-like mycoplasmas attached to the host cell membrane. Smaller web-like structures on the cell surface represent microvilli of the cell. Original magnification 3,000×.Mycoplasmas have
Whither the Ideal RNA Amplification Kit?
Jeff Minerd(jminerd@the-scientist.com) | Mar 13, 2005 | 6 min read
Audrey Player is searching for the ideal RNA amplification protocol.
The Nine Lives of Lab Equipment
Laura Lane(llane@the-scientist.com) | Mar 13, 2005 | 8 min read
Last month Ron Smock, owner of Drug Detection Services, a forensic and criminalistic testing facility in Albuquerque, NM, posted this auction on eBay
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