Tools and Technology

Most Recent

Agilent Launches ChIP-on-Chip

By | December 5, 2005

Chromatin immunoprecipitation (ChIP), or location analysis, is an antibody-based method for identifying the segments of DNA recognized by a particular transcription factor in a native chromatin environment.

0 Comments

GFT NMR Proves Its Structural Genomics Mettle

By | December 5, 2005

G-matrix Fourier transform (GFT) NMR, a technique developed several years ago for rapid collection of nuclear magnetic resonance data, has been used to determine the structures of eight proteins in less than a month.1 "People usually work for many months for one structure. And even a year is not unusual," says coauthor Thomas Szyperski of the University of Buffalo. [see related story, page 36]The work demonstrates for the first time that GFT NMR works on a "real world" scale, meaning a protein c

0 Comments

Mapping MAPK Activation

By | December 5, 2005

are a hot topic these days.

0 Comments

Measuring Protein Concentrations in Live Cells

By | December 5, 2005

data that's essential for mathematical modeling of biological pathways.

0 Comments

Reconstructing Mammalian Cell Lineages

By | December 5, 2005

Adult nematode worms contain 959 somatic cells, and thanks to Nobel laureate John Sulston and colleagues, scientists know the lineage of every one of them.

0 Comments

A cDNA Library, Literally

By | November 21, 2005

Geneticists subject to late-night bouts of inspiration generally have to write down their good ideas.

0 Comments

Columns

By | November 21, 2005

Two independent groups have demonstrated a new method for purifying proteins that may offer a simpler, cheaper alternative to large-scale column purification.

0 Comments

Crystallography for Everyone

By | November 21, 2005

The Bruker AXS Smart Breeze X-ray crystallography system is an instrument that lives up to its name, says Bruker spokesperson Susan Byram.

0 Comments

on Your Screen

By | November 21, 2005

Brian Fisher, curator of entomology at the California Academy of Sciences, has such enthusiasm for ants, he can make you feel guilty over spraying the little devils in your kitchen.

0 Comments

A Crystal Ball for Protein Separations?

By | November 7, 2005

An interdisciplinary team at Rensselaer Polytechnic Institute (RPI) in Troy, NY, has developed a computer program that uses protein structural information to predict how proteins separate on a chromatography column.1 "This is something that is usually done by trial and error, but in this case we've used information from the experiment to build a computer model that enables us to make that prediction," explains coauthor Curt Breneman, a computational chemist at RPI.The technique first takes exper

0 Comments

Popular Now

  1. Man Receives First In Vivo Gene-Editing Therapy
  2. Long-term Study Finds That the Pesticide Glyphosate Does Not Cause Cancer
  3. Researchers Build a Cancer Immunotherapy Without Immune Cells
  4. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

RayBiotech