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tag stem cell trials neuroscience parkinson s disease

Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022 | 4 min read
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Abby Olena, PhD | Aug 30, 2017 | 3 min read
Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.
A pink and blue illustration of the central nervous system, visible through a translucent outline of a human head and shoulders, zooms in to show an illustration of interconnected neurons
Specific Brain Cells Linked to Parkinson’s Disease
Dan Robitzski | May 6, 2022 | 2 min read
Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.
3D illustration showing neurons inside the brain
Experimental Pill to Treat Parkinson’s Is Safe, Trial Finds
Andy Carstens | Jun 10, 2022 | 2 min read
Testing in animals and lab-grown cells suggests the experimental drug could enhance the function of lysosomes within cells.
The Genes of Parkinson’s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011 | 10 min read
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
The Breakthrough Prize ?Trophy
2024 Breakthrough Prizes in Life Sciences
Danielle Gerhard, PhD | Sep 14, 2023 | 10 min read
This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018 | 3 min read
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
3D rendered medical illustration of neurons containing Lewy bodies (small red spheres), accumulated proteins in brain cells that cause degeneration and are linked to Parkinson’s disease.
The Bigger Protein Picture of Designing Parkinson’s Therapeutics
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers highlight protein structure considerations for designing inhibitors that target familial Parkinson’s disease mutations.
New Culprit for Parkinson’s?
Dan Cossins | Oct 16, 2012 | 3 min read
Scientists use human stem cells to show that nuclear defects may play a role in Parkinson’s disease, and suggest a way to reverse the problem.

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