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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Genetic Risk Factors for Breast Cancer Identified

Genetic Risk Factors for Breast Cancer Identified

By | October 23, 2017

Researchers identify 72 novel genetic variants associated with breast cancer risk.

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image: Circadian Gene Linked to Severe Epilepsy in Children

Circadian Gene Linked to Severe Epilepsy in Children

By | October 11, 2017

Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.

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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.

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image: Giants of Circadian Biology Win Nobel Prize

Giants of Circadian Biology Win Nobel Prize

By | October 2, 2017

The award in Physiology or Medicine goes to chronobiologists Jeffrey Hall, Michael Rosbash, and Michael Young.

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image: Booger Bacteria’s Sweet Immune Suppression

Booger Bacteria’s Sweet Immune Suppression

By | September 6, 2017

Sweet taste receptor-activating molecules produced by sinus microbes suppress the local innate immune system in humans.

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image: A Bacterial Messenger Molecule Extends Healthspan

A Bacterial Messenger Molecule Extends Healthspan

By | August 28, 2017

E. coli that make indoles protect older worms, flies, and mice from frailty. 

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