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Illustration of intestine containing pink microbes
Fungal DNA, Cells Found in Human Tumors
Catherine Offord | Sep 30, 2022 | 2 min read
It’s not clear whether, or how, the organisms might play a role in disease pathology.
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan, PhD | Apr 8, 2022 | 5 min read
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
Manipulating the Microbiome to Manage Disease
The Scientist Creative Services Team in collaboration with Tecan | 1 min read
Cammie Lesser will discuss how she turns a probiotic into a drug-delivering machine, while Andrew Y. Koh will describe the connection between the gut microbiota and cancer immunotherapy efficacy.
illustration of a blood vessel
Bacteria in Tumors Promote Metastasis in Mice
Sophie Fessl, PhD | Apr 7, 2022 | 3 min read
Microbes living inside cancer cells may help them spread to distant sites by enhancing the cells’ resistance to mechanical stress, a study shows.
Abstract composition of design object with lines and spheres
Notable Science Quotes
The Scientist | Mar 16, 2022 | 3 min read
Reviving the Cancer Moonshot, disentangling the microbiome's effect in cancer, the observer effect, and more
A Little Help From My Friends: Lessons Learned From Microbiome Metagenomics
The Scientist | 1 min read
Heather Jordan and Jennifer Wargo will discuss how metagenomics studies help uncover new and medically relevant functions of the human microbiome.
Tumor microbiome composite
Could Cancer’s Microbiome Help Diagnose and Treat the Disease?
Jef Akst | Mar 14, 2022 | 10+ min read
A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.
Illustration showing microbial signatures of cancer in the body
Infographic: Putting Cancer’s Unique Microbiomes to Use
Jef Akst | Mar 14, 2022 | 1 min read
From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.
black-and-white image of an open mouth
The Common Mouth Microbe That Keeps Popping Up in Tumors
David Adam | Dec 15, 2021 | 6 min read
Lab studies link the oral bacteria Fusobacterium nucleatum to cancers from the gut to the head and neck. Could targeting the microbe tackle tumors?
salt on a black background
Salty Diet Helps Gut Bugs Fight Cancer in Mice: Study
Sophie Fessl, PhD | Sep 20, 2021 | 4 min read
A high-salt diet suppressed the growth of tumors in a mouse model of melanoma, apparently because of an interplay between the gut microbiome and natural killer cells.
white and yellow colonies growing on a petri dish
Gut Fungi Hamper Radiation Therapy in Mice with Cancer
Rachael Moeller Gorman | Aug 11, 2021 | 3 min read
Depleting intestinal fungi allows radiation to effectively fight cancer, likely because the microbes influence the antitumor immune response.
An illustration of several DNA helices on a light red water color background
Human Blood Harbors Cell-Free Microbial DNA
Abby Olena, PhD | Jul 9, 2021 | 3 min read
After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in plasma samples from healthy people and cancer patients.
an illustration of a mix of different bacteria
Fecal Transplant Could Boost Immunotherapy to Treat Melanoma
Shawna Williams | Feb 12, 2021 | 4 min read
The results from two Phase 1 trials bolster the case that the gut microbiome plays a role in response to the drugs.
Microbial Signatures in Blood Are Associated with Various Cancers
Shawna Williams | Jul 13, 2020 | 2 min read
A study suggests the potential for a noninvasive diagnostic that could detect tumors early and differentiate between disease types.
tweaking microbiome composition reduces colorectal tumor growth in mice
Image of the Day: Tamed Gut Bacteria
Nicoletta Lanese | Aug 8, 2019 | 2 min read
Curbing the growth of harmful bacteria in mouse microbiomes reduces the animals’ incidence of inflammation-related colorectal cancer.
scientist to watch laura bowers
Laura Bowers Works to Sever the Link Between Obesity and Cancer
Shawna Williams | Jul 15, 2019 | 3 min read
The Purdue University nutrition researcher delves into the details of how fat tissue affects tumors.
Cancer-Fighting Chemical Found in Human Skin Bacteria
Diana Kwon | Mar 1, 2018 | 2 min read
A molecule produced by a strain of Staphylococcus epidermis interferes with DNA synthesis.
Microbes Meet Cancer
Kate Yandell | Apr 1, 2016 | 10+ min read
Understanding cancer’s relationship with the human microbiome could transform immune-modulating therapies.
Immune Influence
Kate Yandell | Mar 31, 2016 | 1 min read
In recent years, research has demonstrated that microbes living in and on the mammalian body can affect cancer risk, as well as responses to cancer treatment.
Microbes Play Role in Anti-Tumor Response
Anna Azvolinsky | Nov 5, 2015 | 4 min read
Gut microbiome composition can influence the effectiveness of cancer immunotherapy in mice.
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