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In the largest study of its kind to date, researchers find more than 850 rare, heritable genetic alterations that can predispose humans to cancer.

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image: Is the Interstitium Really a New Organ?

Is the Interstitium Really a New Organ?

By Abby Olena | March 28, 2018

A study confirms that the spaces between cells are fluid-filled, rather than tightly packed with connective tissue, but pathologists say the findings’ implications remain to be seen.

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Testing treatments on mini tumors may save time in identifying which therapies work best, a new study shows.   

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image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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image: DNA Robots Target Cancer

DNA Robots Target Cancer

By Abby Olena | February 12, 2018

Researchers use DNA origami to generate tiny mechanical devices that deliver a drug that cuts off the blood supply to tumors in mice.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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image: Genetic Risk Factors for Breast Cancer Identified

Genetic Risk Factors for Breast Cancer Identified

By Ashley P. Taylor | October 23, 2017

Researchers identify 72 novel genetic variants associated with breast cancer risk.

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image: Vitamin C Depletion Accelerates Leukemia in Mice

Vitamin C Depletion Accelerates Leukemia in Mice

By Aggie Mika | August 21, 2017

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By Aggie Mika | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By Anna Azvolinsky | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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