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image: Double-Edged Enzyme

Double-Edged Enzyme

By Rina Shaikh-Lesko | August 13, 2015

Researchers find evidence to suggest why an enzyme crucial for fighting off malaria infection is linked to a form of lymphoma.


image: Chemical Cocktails Produce Neurons

Chemical Cocktails Produce Neurons

By Kerry Grens | August 6, 2015

Two research groups have devised small-molecule recipes to directly transform fibroblasts into neurons.


image: Cancer-Driving Mutations Common in Normal Skin Cells

Cancer-Driving Mutations Common in Normal Skin Cells

By Anna Azvolinsky | May 21, 2015

A deep-sequencing analysis reveals that non-malignant skin cells harbor many more cancer-driving mutations than previously expected. 


image: New Stem Cell Identified

New Stem Cell Identified

By Anna Azvolinsky | May 6, 2015

Researchers isolate an easy-to-manipulate, stable, and spatially distinct pluripotent cell type.  


image: Personalized Devices Predict Cancer Drug Response

Personalized Devices Predict Cancer Drug Response

By Anna Azvolinsky | April 22, 2015

Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.

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image: Cancer Sequencing Controls

Cancer Sequencing Controls

By Ruth Williams | April 15, 2015

Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.

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image: Clam Cancer Rips Along Atlantic Coast

Clam Cancer Rips Along Atlantic Coast

By Jyoti Madhusoodanan | April 9, 2015

A leukemia that’s killing far-flung populations of softshell clams may be contagious. 


image: Insulin Interference Triggers Cancer-Linked Cachexia

Insulin Interference Triggers Cancer-Linked Cachexia

By Jyoti Madhusoodanan | April 6, 2015

A tumor-secreted protein interferes with insulin signaling to cause cancer-linked muscle wasting in fruit flies. 


image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By Anna Azvolinsky | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 


image: Stem Cells Phone Home

Stem Cells Phone Home

By Jef Akst | February 26, 2015

A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.

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