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image: Personalized Cancer Vaccines

Personalized Cancer Vaccines

By Anna Azvolinsky | April 2, 2015

A dendritic cell vaccine targeting melanoma patients’ tumor-specific mutations can activate a broad range of cancer-fighting T cells. 

2 Comments

image: Stem Cells Phone Home

Stem Cells Phone Home

By Jef Akst | February 26, 2015

A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.

1 Comment

image: Stemming Genetic Changes in Cultured Cells

Stemming Genetic Changes in Cultured Cells

By Ashley P. Taylor | February 25, 2015

Researchers report an association between culture conditions and genetic changes in stem cells over time.

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image: Engineered Biomarkers Could ID Cancer Cells

Engineered Biomarkers Could ID Cancer Cells

By Jenny Rood | February 23, 2015

Scientists develop synthetic blood-based biomarkers to amplify tumor signals in a mouse model.

2 Comments

image: Exploring the Epigenome

Exploring the Epigenome

By Jenny Rood | February 18, 2015

A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.

3 Comments

image: Long-Lived Immunotherapy Stem Cells

Long-Lived Immunotherapy Stem Cells

By Ruth Williams | February 4, 2015

Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.

1 Comment

image: Culturing Changes Cells

Culturing Changes Cells

By Kerry Grens | February 3, 2015

Within days of their transfer to a dish, a certain epigenetic mark vanishes from mouse cells.

2 Comments

image: Benefits of Missing MYC

Benefits of Missing MYC

By Kate Yandell | January 22, 2015

Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.

1 Comment

image: Stem Cell Divisions Help Explain Cancer Risk

Stem Cell Divisions Help Explain Cancer Risk

By Anna Azvolinsky | January 1, 2015

An analysis of 31 tissues finds that random mutations acquired during stem cell divisions correlate with lifetime cancer risk.  

7 Comments

image: Focus on Sex

Focus on Sex

By Molly Sharlach | December 29, 2014

In 2014, new research findings and guidelines brought increased attention to biological differences between males and females.

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