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image: Science Setbacks: 2014

Science Setbacks: 2014

By Molly Sharlach | December 25, 2014

This year in life science was marked by paltry federal funding increases, revelations of sequence contamination, and onerous regulations.

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image: Reprogramming Redux

Reprogramming Redux

By Anna Azvolinsky | December 18, 2014

Can mechanical forces alone be manipulated to create stem-like cells?

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image: New Stem Cell State

New Stem Cell State

By Anna Azvolinsky | December 10, 2014

Through cellular reprogramming, researchers have produced a novel pluripotent mouse stem cell in vitro.

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image: Vanishing Y Chromosomes

Vanishing Y Chromosomes

By Molly Sharlach | December 4, 2014

A new study reveals an association between smoking and rates of Y chromosome loss in blood cells, which may explain elevated cancer risk among male smokers.

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image: Illuminating the Interactome

Illuminating the Interactome

By Molly Sharlach | November 20, 2014

A massive screen yields the most comprehensive map of binary human protein interactions to date.

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image: Modified Yeast Tolerate Alcohol, Heat

Modified Yeast Tolerate Alcohol, Heat

By Kate Yandell | October 2, 2014

Simple changes help yeast thrive in the presence of their own harmful byproducts and could boost biofuel production.

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image: Neural Stem Cells Sprout Long Axons

Neural Stem Cells Sprout Long Axons

By Jyoti Madhusoodanan | August 7, 2014

Early neurons reprogrammed from human skin cells show unprecedented axonal growth in a rat model of spinal cord injury.

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image: Epigenetic Changes Can Cause Cancer

Epigenetic Changes Can Cause Cancer

By Ashley P. Taylor | July 25, 2014

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

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image: A Multi-Cancer Diagnostic?

A Multi-Cancer Diagnostic?

By Kate Yandell | July 14, 2014

Researchers report an ability to detect several types of cancer in blood samples based on signatures of immune response, but some are skeptical about the utility of such a test.

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image: Not All Stem Cells Created Equal

Not All Stem Cells Created Equal

By Anna Azvolinsky | July 2, 2014

Compared to induced pluripotent stem cells generated from somatic cells, stem cells created by nuclear transfer appear to be closer to the genetic state of embryonic cells.

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