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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By Kerry Grens | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Details Published on CRISPR-treated Embryos

Details Published on CRISPR-treated Embryos

By Kerry Grens | August 2, 2017

Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.

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image: Human Genetic Variation May Complicate CRISPR

Human Genetic Variation May Complicate CRISPR

By Ashley Yeager | July 31, 2017

Slight sequence differences confound target sites in precision genome-editing, a study shows.

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image: Zebrafish Embryos Survive Deep Freeze and Quick Thaw

Zebrafish Embryos Survive Deep Freeze and Quick Thaw

By Ashley Yeager | July 28, 2017

In a first, scientists reanimate the fish using embedded gold nanoparticles that heat up cells by absorbing laser light.

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By Ashley P. Taylor | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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image: First Genetic Screen of Pigs Using ENU

First Genetic Screen of Pigs Using ENU

By Ashley Yeager | July 14, 2017

Using the mutagenic chemical N-ethyl-N-nitrosourea, researchers confirm the role of a gene in a piglet deformity and identify potential models for human diseases. 

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image: Mini-Metagenomics Leads to Microbial Discovery

Mini-Metagenomics Leads to Microbial Discovery

By Abby Olena | July 14, 2017

Researchers develop a method that combines the strengths of shotgun metagenomics and single-cell genome sequencing in a microfluidics-based platform.

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image: Behavior Circuits Mapped in Whole Fruit Fly Brain

Behavior Circuits Mapped in Whole Fruit Fly Brain

By Anna Azvolinsky | July 13, 2017

Using machine learning, researchers have created extensive maps of the neuronal circuits associated with social and locomotion behaviors in the fruit fly. 

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image: Anti-CRISPR Protein Reduces Off-Target Effects

Anti-CRISPR Protein Reduces Off-Target Effects

By Diana Kwon | July 12, 2017

AcrIIA4, an inhibitor protein from the Listeria bacteriophage, can block DNA from binding to Cas9 during genome editing.

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