cell & molecular biology, genetics

The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.

Meet some of the people featured in the September 2020 issue of The Scientist.

Working with a virus that infects bacteria, the Stanford University biochemist and developmental biologist helped to develop a way to stitch DNA together, a discovery that gave rise to genetic engineering.

Wing development in females is environmentally controlled, but in males, an insertion on the sex chromosome appears to dictate whether the insects grow wings, according to a study.

The accumulation of zombie-like cells seems to accelerate aging and promote aging-related disease. Researchers are trying to figure out how.

Scientists carve the shapes from piles of frog cells, like a sculptor building a statue.

The announcement by Novartis, the maker of Zolgensma, has drawn mixed reactions from the spinal muscular atrophy community.

Trophoblasts, collected from the mother during a blood draw, can determine fetal genetic abnormalities currently diagnosed through amniocentesis or chorionic villi sampling.

Cardiomyocytes made from iPSCs aboard the International Space Station had upregulated mitochondrial functioning.

The latest restrictions require scientists to submit more comprehensive grant applications, and those applications will go through more stringent ethics reviews.

The Carnegie Mellon computational biologist thinks machine learning algorithms can direct high-throughput experiments to solve the field’s unanswered questions.

Researchers treat mice with retinitis pigmentosa using a gene therapy that reduces cone loss.

Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.

Viruses that infect plants and occasionally insects appear to cause infection with a divide-and-conquer strategy, multiplying separate segments of genetic material in different host cells.

A study underscores the importance of Dna2 in maintaining the integrity of the genetic code.

A study on yeast illuminates how insertions may occur.

This could account for some reproducibility problems in cell line research, according to the authors of a comprehensive analysis of HeLa variants.

Two studies contest the idea that the noncoding sequences are just “junk DNA,” demonstrating that they play important roles in the regulation of cell growth.

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.