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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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image: Pathway to Polio Virulence Revealed

Pathway to Polio Virulence Revealed

By | March 23, 2017

Using epidemiological and laboratory data, scientists have mapped out a sequence of mutations through which the attenuated oral polio vaccine reverts to a virulent virus.

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Mitochondrial DNA polymerase is necessary for the destruction of paternal mtDNA in fruit fly sperm, scientists show.

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image: Inflammation Drives Gut Bacteria Evolution

Inflammation Drives Gut Bacteria Evolution

By | March 16, 2017

Viruses within Salmonella rapidly spread genes throughout the bacterial population during a gut infection, scientists show.

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Proteins with unstable 3-D structures help the microscopic animals withstand drying.

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image: Five More Synthetic Yeast Chromosomes Completed

Five More Synthetic Yeast Chromosomes Completed

By | March 9, 2017

Members of the Synthetic Yeast Genome Project have synthesized five additional yeast chromosomes from scratch. 

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image: Cortical Interneurons Show Layer-Specific Activities

Cortical Interneurons Show Layer-Specific Activities

By | March 2, 2017

Researchers examine the firing patterns of interneurons throughout all layers of the somatosensory cortices of alert mice.  

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image: How Bacteria Interfere with Insect Reproduction

How Bacteria Interfere with Insect Reproduction

By | February 28, 2017

Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.

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image: An Aging-Related Effect on the Circadian Clock

An Aging-Related Effect on the Circadian Clock

By | February 21, 2017

Stress-related genes may be preferentially and rhythmically expressed as part of the circadian rhythms of older fruit flies, researchers report.  

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