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The genome of an infant who lived in Alaska thousands of years ago represents a previously unknown group of humans called Ancient Beringians, who share a common lineage with other Native Americans. 

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By Abby Olena | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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image: The Biggest DNA Origami Structures Yet

The Biggest DNA Origami Structures Yet

By Abby Olena | December 6, 2017

Three new strategies for using DNA to generate large, self-assembling shapes create everything from a nanoscale teddy bear to a nanoscale Mona Lisa.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Six-Letter DNA Alphabet Produces Proteins in Cells

Six-Letter DNA Alphabet Produces Proteins in Cells

By Ruth Williams | November 29, 2017

Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By Ruth Williams | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Hormone Loss Prevents Obesity and Diabetes in Mice

Hormone Loss Prevents Obesity and Diabetes in Mice

By Abby Olena | November 6, 2017

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

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image: The Genetic Strategies of Dealing with High Altitude

The Genetic Strategies of Dealing with High Altitude

By Abby Olena | November 2, 2017

Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.

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image: Corals’ pH Sensor Identified

Corals’ pH Sensor Identified

By Ashley P. Taylor | November 1, 2017

Soluble adenylyl cyclase measures and responds to pH changes in coral cells, but whether it can help the animals withstand ocean acidification is not yet known.

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