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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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image: Can Young Stem Cells Make Older People Stronger?

Can Young Stem Cells Make Older People Stronger?

By | December 11, 2017

Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: Genetic Risk Factors for Breast Cancer Identified

Genetic Risk Factors for Breast Cancer Identified

By | October 23, 2017

Researchers identify 72 novel genetic variants associated with breast cancer risk.

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A new study identifies microorganisms residing in the human fallopian tubes and uterus, but some researchers are skeptical of the findings. 

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image: Cesarean Section Results in Heavier Mouse Pups

Cesarean Section Results in Heavier Mouse Pups

By | October 11, 2017

Vaginal birth leads to changes in the development of offsprings’ microbiomes not seen among mice born via C-section, which researchers suspect might contribute to the weight differences.

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Combined transcription and genome data from multiple tissues in hundreds of human donors reveal links between genotype and gene expression across the body.

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