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Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

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image: Circadian Gene Linked to Severe Epilepsy in Children

Circadian Gene Linked to Severe Epilepsy in Children

By Diana Kwon | October 11, 2017

Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.

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image: Duplicated Genes May Reduce Resilience in Yeast

Duplicated Genes May Reduce Resilience in Yeast

By Diana Kwon | February 14, 2017

Researchers find that some duplicated yeast genes develop dependency—the loss of one copy leads to the failure of the other.

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image: Geography of Genetic Diversity

Geography of Genetic Diversity

By Rina Shaikh-Lesko | September 29, 2016

Mammals and amphibians show greater intraspecific genetic diversity in the tropics compared with temperate regions.

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image: Blocking a Stress-Related Gene Relieves Chronic Pain

Blocking a Stress-Related Gene Relieves Chronic Pain

By Anna Azvolinsky | February 10, 2016

Inhibiting the activity of a protein involved in the body’s stress response can ease chronic pain in mice.

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image: Mosaic Mutations

Mosaic Mutations

By Kate Yandell | July 31, 2014

Some genetic abnormalities that appear to have sprung up independently in children are in fact present in a portion of their parents’ cells.

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image: <em>Drosophila</em>’s New Genes

Drosophila’s New Genes

By Jef Akst | January 23, 2014

An analysis of the transcriptomes of several fruit fly strains reveals dozens of possible de novo genes in each.

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image: Daytime Sleep Alters Human Transcriptome

Daytime Sleep Alters Human Transcriptome

By Jef Akst | January 20, 2014

A mistimed sleep cycle drastically reduces the number of genes that are expressed in a 24-hour rhythm.

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image: Genetic Roots of the Ashkenazi Jews

Genetic Roots of the Ashkenazi Jews

By Kate Yandell | October 8, 2013

Most Ashkenazi Jews, traditionally believed to have descended from the ancient tribes of Israel, may in fact be maternally descended from prehistoric Europeans.

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image: Single-Gene Knockout Collection Created

Single-Gene Knockout Collection Created

By Kerry Grens | August 25, 2013

Researchers develop several thousand haploid human cell lines, each with a different gene mutant.

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