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tag yeast stem cells genetics cell molecular biology

Yeast Made to Harvest Light Hint at Evolution’s Past
Kamal Nahas, PhD | Feb 21, 2024 | 6 min read
Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
A Molecular Switch for Bone Loss
Mariella Bodemeier Loayza Careaga, PhD | Jan 23, 2024 | 4 min read
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
This is an image of a bioluminescent from gene expression reporter in stem cells from a rhinoceros.
A Stem Cell Zoo Reveals Surprising Differences in Embryogenesis
Ida Emilie Steinmark, PhD | Sep 1, 2023 | 2 min read
By comparing stem cells from six mammals of different sizes, scientists discovered stark differences in embryonic development paces.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Unlocking the Secrets within Cells Using Next Generation Sequencing
Unlocking the Secrets within Cells Using Next Generation Sequencing 
The Scientist | Sep 25, 2023 | 1 min read
Next generation sequencing (NGS) core facility scientists and researchers discuss their latest work exploring novel cancer models and stem cells in space.
Image of yeast cells
Yeast Cells Reconfigure Their Metabolomes to Live Longer
Danielle Gerhard, PhD | Jul 5, 2023 | 2 min read
Yeast cells share metabolites through extracellular space to extend the lifespan of the entire community.
Genotoxic Effects of Base and Prime Editing
Kamal Nahas, PhD | Jan 12, 2024 | 5 min read
A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate. 
Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.
Stem Cell Lines Riddled With Undetected Mutations
Dan Robitzski | Aug 12, 2022 | 4 min read
Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.

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