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tag disease medicine neuroscience ecology stem cells

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.
Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022 | 4 min read
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Exploring the Past, Present, and Future of Brain Organoids 
Niki Spahich, PhD | Feb 18, 2024 | 5 min read
Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.
A three-dimensional rendered image of neuron cell network on black background.
Assembloids Unlock the Roles of Key Neurodevelopment Disease Genes
Aparna Nathan, PhD | Sep 27, 2023 | 3 min read
Brain-like tissue grown in a dish mimics critical periods for development and reveals how it can go wrong.
You Are When You Eat
Iris Kulbatski, PhD | Nov 20, 2023 | 3 min read
Intermittent fasting regulates biological time and improves disrupted sleep in an Alzheimer’s disease model.
Novelty Activates a Long Noncoding RNA for Spatial Learning in Mice
Shelby Bradford, PhD | Feb 6, 2024 | 4 min read
Genes activated in new environments include those used during development.
Glimpses of stem cell medicine
Alison McCook | Mar 31, 2006 | 2 min read
After three days of discussions about stem cell machinery, the organizers concluded the linkurl:Keystone meeting;http://www.keystonesymposia.org/Meetings/ViewMeetings.cfm?MeetingID=786 on stem cell biology today by treating participants to data showing what these cells can already do in humans. These efforts appear not quite as differentiated as stem cells themselves, but are hopefully on their way to becoming so. Tonight, Michele De Luca from the Veneto Eye Bank Foundation and the University o
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
A reprogrammed astrocyte that can regenerate functional neurons.
Reprogramming Astrocytes: Unlocking DLX2’s Potential to Mend the Brain
Nele Haelterman, PhD | Jan 23, 2023 | 3 min read
Scientists discover how to convert the brain’s glial cells into multipotent neural stem cells.

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