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tag oligodendrocyte parkinson s disease culture

march 2019 the scientist profile
Master Decoder: A Profile of Kári Stefánsson
Anna Azvolinsky | Mar 1, 2019 | 9 min read
A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.
Glia Guru
Anna Azvolinsky | May 1, 2017 | 9 min read
Ben Barres recast glial cells from supporting actors to star performers, crucial for synaptic plasticity in the brain and for preventing neurodegenerative disorders.
Into the Limelight
Kate Yandell | Oct 1, 2015 | 8 min read
Glial cells were once considered neurons’ supporting actors, but new methods and model organisms are revealing their true importance in brain function.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Gene Therapy Targets Canavan Disease
Douglas Steinberg | Sep 16, 2001 | 6 min read
The Canavan trial signals a new phase in a 10-year offensive that gene therapy researchers have waged against neurodegenerative disorders.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Pelizaeus-Merzbacher disease neural stem cell transplantation
Neural Stem Cell Transplantation Crawls Toward the Clinic
Ashley P. Taylor | Oct 29, 2019 | 9 min read
Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.
Chemyx: Tracing Fibers - From DiI to Modern Methods
Chemyx Inc. | Apr 24, 2018 | 3 min read
Visualizing neuronal connections is highly important for understanding brain organization and pathophysiology. However, this data has historically been obtained through invasive and often terminal procedures. Technological advances have permitted the development of a new era of neuroanatomical tracing techniques.   
Alzheimer Research Joins the Mainstream
Christine Bahls | Jan 20, 2002 | 5 min read
In 1977, Alzheimer Disease researcher Peter Davies spoke with some neurologists about his work, which he began a year earlier. "One [neurologist] said, 'This is lovely..., but why don't you work on something that is more common?'" he remembers. Davies says the comment epitomized scientists' then-dismissive attitude about Alzheimer Disease (AD). When Alois Alzheimer first identified this memory-destroying disorder in 1907, his patient was a 50-year-old woman; a very early age, as researchers now

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