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image: Monitoring Mutations with Microfluidics

Monitoring Mutations with Microfluidics

By Ruth Williams | March 15, 2018

A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  


image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  


Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.


image: Corals’ pH Sensor Identified

Corals’ pH Sensor Identified

By Ashley P. Taylor | November 1, 2017

Soluble adenylyl cyclase measures and responds to pH changes in coral cells, but whether it can help the animals withstand ocean acidification is not yet known.


With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.


image: A Potential Remedy for the Aging Brain

A Potential Remedy for the Aging Brain

By Aggie Mika | August 8, 2017

In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 


A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.


image: Gut Feeling

Gut Feeling

By Ruth Williams | June 22, 2017

Sensory cells of the mouse intestine let the brain know if certain compounds are present by speaking directly to gut neurons via serotonin.


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