genetics & genomics, cell & molecular biology

Family members of Lacks, the donor behind the widely used HeLa cell line, are planning to sue Johns Hopkins University.

The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.

The tails of polygamous deer mice sperm have longer midsections than the sperm tails of monogamous individuals of a similar species, and this correlates with improved swimming and competitive ability.

Researchers launch an initiative to generate a complete atlas of all cells in the human body.

NSAIDs reduce this "parainflammation," hinting at how they help lower cancer risk.

Traditional stop codons have a double meaning in the protozoans' mRNA, sometimes calling for an amino acid during translation.

Newly developed techniques from four different groups rely on the same basic steps to track translation in live cells.

Precursor T cells bearing the same antigen receptor adopt two different fates in mice.

Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.

Researchers repurpose a bacterial immune system to be a molecular recording device.

Elaine Fuchs has worked on adult stem cells since before they were so named, figuring out how multipotent epidermal cells renew or turn into skin or hair follicles.

Rockefeller University researcher Elaine Fuchs on being a woman in science and her contributions to the burgeoning field of reverse genetics

Methylation on adenine bases is involved in the dampening of gene expression in mammalian cells, according to a study.

Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.

A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.

Genetic evidence suggests that overactive synaptic pruning drives development of schizophrenia.

Key Alzheimer’s disease–related protein may be a transcriptional regulator.

After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.

Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years.

Meet Wolf Reik, August Profilee and Babraham Institute director of research.