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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By Anna Azvolinsky | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

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image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By Ruth Williams | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By Abby Olena | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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image: Should Healthy People Have Their Exomes Sequenced?

Should Healthy People Have Their Exomes Sequenced?

By Ruth Williams | March 24, 2017

With its announced launch of a whole-exome sequencing service for apparently healthy individuals, Ambry Genetics is the latest company to enter this growing market. But whether these services are useful for most people remains up for debate.  

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Mitochondrial DNA polymerase is necessary for the destruction of paternal mtDNA in fruit fly sperm, scientists show.

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Proteins with unstable 3-D structures help the microscopic animals withstand drying.

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image: Five More Synthetic Yeast Chromosomes Completed

Five More Synthetic Yeast Chromosomes Completed

By Anna Azvolinsky | March 9, 2017

Members of the Synthetic Yeast Genome Project have synthesized five additional yeast chromosomes from scratch. 

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image: How Bacteria Interfere with Insect Reproduction

How Bacteria Interfere with Insect Reproduction

By Ruth Williams | February 28, 2017

Scientists identify the genes responsible for bacteria-controlled sterility in arthropods.

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image: An Aging-Related Effect on the Circadian Clock

An Aging-Related Effect on the Circadian Clock

By Anna Azvolinsky | February 21, 2017

Stress-related genes may be preferentially and rhythmically expressed as part of the circadian rhythms of older fruit flies, researchers report.  

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