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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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image: Learning Opens the Genome

Learning Opens the Genome

By | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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Researchers identify patterns of neural activity ranging from a few days to four weeks in individuals with epilepsy.

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image: Primary Cilia in Neurons Linked to Obesity

Primary Cilia in Neurons Linked to Obesity

By | January 8, 2018

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 

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image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 

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Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

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image: Can Young Stem Cells Make Older People Stronger?

Can Young Stem Cells Make Older People Stronger?

By | December 11, 2017

Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 

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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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  1. How Gaining and Losing Weight Affects the Body
    Daily News How Gaining and Losing Weight Affects the Body

    Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

  2. That Other CRISPR Patent Dispute
    Daily News That Other CRISPR Patent Dispute

    The Broad Institute and Rockefeller University disagree over which scientists should be named as inventors on certain patents involving the gene-editing technology.

  3. Neurons Use Virus-Like Proteins to Transmit Information
  4. EPO Revokes Broad’s CRISPR Patent
    The Nutshell EPO Revokes Broad’s CRISPR Patent

    Shortly after ruling out the earliest priority dates on a foundational patent for CRISPR gene-editing technology, the European Patent Office rescinded the patent entirely—and more are likely to follow.

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