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A new statistical method finds that many genetic variants used to determine trait-disease relationships may have additional effects that GWAS analyses don’t pick up.

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Thousands of axons grew from the transplants and connected to damaged primate tissue, the first such demonstration in primates.

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image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

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image: Can Young Stem Cells Make Older People Stronger?

Can Young Stem Cells Make Older People Stronger?

By Shawna Williams | December 11, 2017

Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By Ruth Williams | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Circadian Gene Linked to Severe Epilepsy in Children

Circadian Gene Linked to Severe Epilepsy in Children

By Diana Kwon | October 11, 2017

Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By Ashley P. Taylor | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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