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image: Can Young Stem Cells Make Older People Stronger?

Can Young Stem Cells Make Older People Stronger?

By | December 11, 2017

Small trials using younger donors and elderly recipients hint that mesenchymal stem cell transfers might reduce frailty. 

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Circadian Gene Linked to Severe Epilepsy in Children

Circadian Gene Linked to Severe Epilepsy in Children

By | October 11, 2017

Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.

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Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.

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image: A Potential Remedy for the Aging Brain

A Potential Remedy for the Aging Brain

By | August 8, 2017

In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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image: Deep Brain Stimulation Without Surgery

Deep Brain Stimulation Without Surgery

By | June 1, 2017

Using interfering high-frequency currents applied to the surface of the mouse skull, scientists can noninvasively target brain regions buried below the cortical surface. 

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image: Blood Stem Cells Grown in the Lab

Blood Stem Cells Grown in the Lab

By | May 17, 2017

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

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