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image: Mini-Metagenomics Leads to Microbial Discovery

Mini-Metagenomics Leads to Microbial Discovery

By | July 14, 2017

Researchers develop a method that combines the strengths of shotgun metagenomics and single-cell genome sequencing in a microfluidics-based platform.

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image: Anti-CRISPR Protein Reduces Off-Target Effects

Anti-CRISPR Protein Reduces Off-Target Effects

By | July 12, 2017

AcrIIA4, an inhibitor protein from the Listeria bacteriophage, can block DNA from binding to Cas9 during genome editing.

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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The discovery of peptides, enzymes, and other gene products that confer antibiotic resistance could give clues to how it develops.

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image: Genes Tied to Wasps Recognizing Faces

Genes Tied to Wasps Recognizing Faces

By | June 14, 2017

The brains of Polistes paper wasps express different genes when identifying faces than when distinguishing between simple patterns, a study finds.

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image: Mammals May Have a 12-Hour Clock

Mammals May Have a 12-Hour Clock

By | June 6, 2017

Data point to peaks in gene expression in the morning and evening that are distinct from day-night circadian cycles.

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image: CRISPR Corrects Duchenne-Causing Mutations

CRISPR Corrects Duchenne-Causing Mutations

By | April 12, 2017

Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.

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Octopus, cuttlefish, and squid extensively edit messenger RNAs in an evolutionarily conserved process. 

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image: Cross-Sample Sequencing Contamination Galore

Cross-Sample Sequencing Contamination Galore

By | April 5, 2017

Scientists conducting a large-scale, comparative transcriptomics project have inadvertently highlighted widespread contamination in sequencing data.

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image: CRISPR Screen Detects Functional Gene Regulation

CRISPR Screen Detects Functional Gene Regulation

By | April 3, 2017

A CRISPR-Cas9–based method probes the regulatory roles of noncoding DNA sequences.

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