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image: “Retired” Mice Find New Life as Top Models for Autism

“Retired” Mice Find New Life as Top Models for Autism

By Jessica Wright | January 29, 2018

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.


image: Learning Opens the Genome

Learning Opens the Genome

By Ruth Williams | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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image: Opinion: Label Drugs That Are Tested on Animals

Opinion: Label Drugs That Are Tested on Animals

By Shaun Khoo | January 16, 2018

Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.

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Researchers identify patterns of neural activity ranging from a few days to four weeks in individuals with epilepsy.


image: Primary Cilia in Neurons Linked to Obesity

Primary Cilia in Neurons Linked to Obesity

By Abby Olena | January 8, 2018

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 


The goal is to house patients’ follicles in a specially designed tissue matrix and reinsert them after treatment.


image: Photos of the Year

Photos of the Year

By Katarina Zimmer | December 25, 2017

From a plastic-munching coral to see-through frogs, here are The Scientist’s favorite images from 2017.


image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By Abby Olena | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 


Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.


Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.


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