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Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.

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The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

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image: New Insights to Improve CAR T Cells’ Safety

New Insights to Improve CAR T Cells’ Safety

By Vicki Brower | June 5, 2018

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

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image: Preterm Labor May Be Sparked by Fetal Immune Reaction

Preterm Labor May Be Sparked by Fetal Immune Reaction

By Ruth Williams | April 25, 2018

Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  

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image: Some Antibiotics Rev Up Host Immune Response to Viruses

Some Antibiotics Rev Up Host Immune Response to Viruses

By Shawna Williams | April 9, 2018

The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.

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image: Opinion: We Have Been Naive About Naive T Cells

Opinion: We Have Been Naive About Naive T Cells

By Theo van den Broek, José A.M. Borghans, and Femke van Wijk | April 6, 2018

Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.

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The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.

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image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.

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The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.

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