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image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.

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The discovery reveals the role of a growth factor and endothelial cells in thymus repair, and could have implications for chemotherapy and radiation patients’ recovery following treatment.

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image: Antiviral Immunotherapy Comes of Age

Antiviral Immunotherapy Comes of Age

By Lucas Laursen | December 4, 2017

T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections. 

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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image: Booger Bacteria’s Sweet Immune Suppression

Booger Bacteria’s Sweet Immune Suppression

By Ruth Williams | September 6, 2017

Sweet taste receptor-activating molecules produced by sinus microbes suppress the local innate immune system in humans.

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image: An Immunological Timeline for Pregnancy

An Immunological Timeline for Pregnancy

By Catherine Offord | September 1, 2017

A new study uses blood samples from pregnant women to track changes in the immune system leading up to birth, and predicts gestational age from the mothers’ immune signatures.

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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By Catherine Offord | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By Ashley P. Taylor | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Mammalian Immunity: What’s RNAi Got to Do with It?

Mammalian Immunity: What’s RNAi Got to Do with It?

By Shawna Williams | July 21, 2017

A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.

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