cancer

Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.  

A career-altering experience as a cancer patient motivated one researcher to design more potent immunotherapies.

A guide to mRNA-based cancer vaccines and where they’re headed next

A key mutation turns healing cells into cancer promoters.

Probing the protein landscape in lung cancers reveals new therapeutic insights.

The Scientist spoke with University of Liverpool aging and longevity researcher João Pedro de Magalhães about how human biases can influence scientific priorities and outcomes in genetics.

The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.

In a small clinical study, focusing ultrasound beams on tumors in patients’ brains helped open the blood-brain barrier to facilitate drug delivery.

Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.

A high-salt diet suppressed the growth of tumors in a mouse model of melanoma, apparently because of an interplay between the gut microbiome and natural killer cells.

A new platform enables screening a wide range of combination anticancer therapeutics in a matter of days, which may translate to personalized therapeutic regimens for patients in less time.

A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.

Heated gold nanoparticles unleash the therapeutic activity of engineered CAR T cells.

Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.