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cancer

Mammary tumor organoids undergo a radical shape shift when treated with a microRNA.
Organoid Shape Identifies Potential Cancer Drugs
Roni Dengler, PhD | Aug 3, 2021 | 3 min read
An unusual drug screen takes advantage of “porcupine-like” structures of cancer cells in 3D organoids.
visualization of p53 protein interacting with its inhibitors MDM2 and MDMX
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
Marcus A. Banks | Jul 29, 2021 | 4 min read
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
Analyzing Biological Systems with Flow Cytometry
The Scientist Creative Services Team in collaboration with Beckman Coulter Life Sciences | 1 min read
Single-cell analysis provides a superior view of heterogeneous cell populations.
streaks of blue and green from a fluorescent chromosome mapping technique
Optical Genome Mapping Works Well in Detecting Cancer Risk
Marcus A. Banks | Jul 22, 2021 | 3 min read
The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies.
an aerial photo of the University of Hawai'i Cancer Center
Hawai‘i Legislature Terminates Tenured Professor’s Position
Christie Wilcox, PhD | Jul 21, 2021 | 3 min read
Thanks to administrative shuffling, professor Carl-Wilhelm Vogel remains employed at the University of Hawai‘i despite the removal of his position in the new state budget, but the university’s faculty union says lawmakers might have crossed a legal line.
Enhancing the Efficacy of CAR-T Cell Therapies
The Scientist Creative Services Team in Collaboration with IsoPlexis | 1 min read
Jessica Morris will discuss strategies to improve CAR-T cell targeting, activation, and killing capabilities.
black mice in clear plastic cages with bedding
Australian Research Faces Impending Scarcity of Lab Rodents
Bianca Nogrady | Jul 20, 2021 | 7 min read
The Australian biomedical research community is stunned by the announced wind-down of the country’s biggest supplier of mice and rats.
Undone Proteins Take Out Bladder Cancer
Roni Dengler, PhD | Jul 20, 2021 | 3 min read
An unfolded protein found in human milk shows promise in early clinical trials to treat bladder cancer.
Improving Cancer Immunotherapy with Anti-Cancer Adenoviruses
The Scientist and IsoPlexis | 1 min read
Researchers use a mesenchymal stromal cell-based vector to deliver multiple viruses simultaneously to improve CAR-T cell anti-tumor activity.
Homing Technology Delivers Therapy to Cancerous Bone
Roni Dengler, PhD | Jul 19, 2021 | 5 min read
A clever approach to modifying already existing cancer therapies may be a game changer for treating metastatic breast cancer.
A false-colored micrograph showing swirls of yellow, red, and magenta cells
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Sophie Fessl, PhD | Jul 16, 2021 | 6 min read
Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.
Introducing Cell Culture Application-Specific Fetal Bovine Serum Products
The Scientist Creative Services Team in collaboration with MilliporeSigma | 2 min read
A cost-effective fetal bovine serum product line is tailored for individual cell culture needs.  
Antibiotic-Linked Antibody Attacks Cancer’s Sinister Neighbor Cells
Roni Dengler, PhD | Jul 14, 2021 | 2 min read
An unexpected and unprecedented finding may lead to improved cancer therapies.
An illustration of several DNA helices on a light red water color background
Human Blood Harbors Cell-Free Microbial DNA
Abby Olena, PhD | Jul 9, 2021 | 3 min read
After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in plasma samples from healthy people and cancer patients.
Measuring Metabolites to Prevent, Diagnose, and Treat Cancer
Niki Spahich, PhD | 1 min read
Metabolomics research highlights molecules important for cancer prevention, diagnosis, and treatment.
a man in a white t-shirt and face mask receives a bandage on his arm from a clinician wearing blue gloves and a plastic face shield
COVID-19 Vaccines Work in People with Cancer: Study
Marcus A. Banks | Jun 25, 2021 | 4 min read
Moderna’s, Pfizer’s, and Johnson & Johnson’s shots all offered protection against the virus regardless of cancer type, although slightly less so in people with blood cancer.
a leopard gecko with an unusually yellow body
“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas
Christie Wilcox, PhD | Jun 24, 2021 | 6 min read
The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist and Thermo Fisher Scientific | 1 min read
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
photograph of john pawalek in a navy blue suit and red tie
John Pawelek, Who Explored the Causes of Metastasis, Dies at 79
Marcus A. Banks | Jun 22, 2021 | 2 min read
The Yale School of Medicine cancer researcher doggedly pursued the question of how cancer spreads.
illustrations of cancer cells dividing in pink tones
Cancer Metastasizes Via Fusion of Tumor and Immune Cells: Study
Marcus A. Banks | Jun 17, 2021 | 3 min read
Researchers say evidence of hybridization between leukocytes and cancer indicates that this is a primary means of metastasis. Others disagree.
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