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What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps.

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Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.

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The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

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image: New Insights to Improve CAR T Cells’ Safety

New Insights to Improve CAR T Cells’ Safety

By Vicki Brower | June 5, 2018

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

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The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.

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image: Could a Dose of Sunshine Make You Smarter?

Could a Dose of Sunshine Make You Smarter?

By Ruth Williams | May 17, 2018

Moderate ultraviolet light exposure boosts the brainpower of mice thanks to increased production of the neurotransmitter glutamate.  

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image: RNA Moves a Memory From One Snail to Another

RNA Moves a Memory From One Snail to Another

By Ashley Yeager | May 14, 2018

Injecting molecules from a sea slug that received tail shocks into one that didn’t made the recipient animal behave more cautiously. 

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image: Worms’ Magnetic Sense Questioned

Worms’ Magnetic Sense Questioned

By Abby Olena | April 25, 2018

Unsuccessful attempts to reproduce the results of a 2015 study reporting that C. elegans orient themselves by Earth’s magnetic field spark debate among researchers.

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image: Preterm Labor May Be Sparked by Fetal Immune Reaction

Preterm Labor May Be Sparked by Fetal Immune Reaction

By Ruth Williams | April 25, 2018

Immune cells targeting maternal antigens are abundant in the blood of premature infants, suggesting fetal intolerance of mom may instigate early labor.  

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image: Some Antibiotics Rev Up Host Immune Response to Viruses

Some Antibiotics Rev Up Host Immune Response to Viruses

By Shawna Williams | April 9, 2018

The antimicrobial drug neomycin protects mice from some viral infections, complicating the picture of the relationship between antibiotics and susceptibility to viruses.

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