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image: Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys

Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys

By Sukanya Charuchandra | June 20, 2018

The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  

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What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps.

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Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.

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The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.

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Researchers find that conserving marsupials on a predator-free island dampens their avoidance behaviors, which could mean trouble for their reintroduction to mainland Australia.

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image: New Insights to Improve CAR T Cells’ Safety

New Insights to Improve CAR T Cells’ Safety

By Vicki Brower | June 5, 2018

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

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image: Cell Transplant Trial for Spinal Injury Is Safe

Cell Transplant Trial for Spinal Injury Is Safe

By Ruth Williams | June 1, 2018

The first human experiment with neural precursor cells implanted to treat chronic spinal cord injury suggests the procedure is safe, and hints at a small benefit.  

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image: Human-Specific Genes Implicated in Brain Size

Human-Specific Genes Implicated in Brain Size

By Abby Olena | May 31, 2018

Three members of a gene family called NOTCH2NL may have been involved in the evolution of humans’ big cortex.

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Genetic adaptations for human brain development also make us vulnerable to Alzheimer’s disease, according to a new study.  

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The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.

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