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What we can know about biology before the last universal common ancestor is limited—and we should be circumspect in filling in the gaps.

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image: Opinion: Three-Parent Embryos—A Slippery Slope?

Opinion: Three-Parent Embryos—A Slippery Slope?

By John D. Loike and Alan Kadish | June 14, 2018

The use of pronuclear transfer to treat infertility must first be backed by evidence it can work in cases where parents seek to avoid mitochondrial mutations.

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Computational biologists are optimistic that the purchase of the world’s largest hub for open-source computer code will not affect the way they use GitHub for science.

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image: New Insights to Improve CAR T Cells’ Safety

New Insights to Improve CAR T Cells’ Safety

By Vicki Brower | June 5, 2018

Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.

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image: Opinion: How to Use Mobile Apps for Immunohistochemistry

Opinion: How to Use Mobile Apps for Immunohistochemistry

By Alexander E. Kalyuzhny | May 25, 2018

This guide for apps comes from personal experience testing various programs aimed to improve productivity or to help with selecting reagents.

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image: Scientist Who Received Millions From NIH Leaves Alabama Posts

Scientist Who Received Millions From NIH Leaves Alabama Posts

By Ivan Oransky, Retraction Watch | May 24, 2018

An investigation finds 20 papers by Santosh Katiyar, who studied alternative treatments for cancer, include image manipulation.

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Researchers have been using ultrasound to control brain activity, but studies in mice and guinea pigs show it also stimulates the auditory system, presenting a confounder for direct neural stimulation.

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Determining which products of advanced biotechnology are deserving of legal protections is essential to our own social architecture.

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image: Opinion: We Must Demand Evidence of Peer Review

Opinion: We Must Demand Evidence of Peer Review

By Nikolai Slavov | May 21, 2018

Peer review varies in quality and thoroughness. Making it publicly available could improve it.

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image: Opinion: How We Found a New Way to Detect “Hidden Sharks”

Opinion: How We Found a New Way to Detect “Hidden Sharks”

By Stefano Mariani and Judith Bakker | May 7, 2018

Given the speed and efficiency of environmental (eDNA) sampling, a much larger portion of the sea can be screened, in a shorter time, for patterns of diversity.

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