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image: Six-Letter DNA Alphabet Produces Proteins in Cells

Six-Letter DNA Alphabet Produces Proteins in Cells

By Ruth Williams | November 29, 2017

Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

1 Comment

image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By Ruth Williams | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Hormone Loss Prevents Obesity and Diabetes in Mice

Hormone Loss Prevents Obesity and Diabetes in Mice

By Abby Olena | November 6, 2017

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

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image: The Genetic Strategies of Dealing with High Altitude

The Genetic Strategies of Dealing with High Altitude

By Abby Olena | November 2, 2017

Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.

2 Comments

image: Corals’ pH Sensor Identified

Corals’ pH Sensor Identified

By Ashley P. Taylor | November 1, 2017

Soluble adenylyl cyclase measures and responds to pH changes in coral cells, but whether it can help the animals withstand ocean acidification is not yet known.

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image: Opinion: How to Define Cell Type

Opinion: How to Define Cell Type

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

1 Comment

image: RNA Editing Possible with CRISPR-Cas13

RNA Editing Possible with CRISPR-Cas13

By Ruth Williams | October 25, 2017

Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells.

3 Comments

image: The Weird Growth Strategy of Earth’s First Trees

The Weird Growth Strategy of Earth’s First Trees

By Shawna Williams | October 24, 2017

Ancient fossils reveal how woodless trees got so big: by continuously ripping apart their xylem and knitting it back together.

1 Comment

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