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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Genetic Risk Factors for Breast Cancer Identified

Genetic Risk Factors for Breast Cancer Identified

By | October 23, 2017

Researchers identify 72 novel genetic variants associated with breast cancer risk.

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image: Vitamin C Depletion Accelerates Leukemia in Mice

Vitamin C Depletion Accelerates Leukemia in Mice

By | August 21, 2017

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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image: Opinion: Biobanking Has a Consent Dilemma

Opinion: Biobanking Has a Consent Dilemma

By | July 25, 2017

Is the deep uncertainty surrounding fundamental legal and ethical norms putting biobanks in a precarious position? 

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