disease & medicine

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A bioengineered heart made of pig and synthetic tissues beats like the real thing.

With more than 6,000 cases of the 2019-nCoV virus confirmed, researchers are hoping that studying the pathogen in the lab will help stop the outbreak.

A combination of two drugs appears to restore cartilage in rats.

A polymer tube regenerates damaged nerves in monkeys, restoring near full functionality.

EcoHealth Alliance President Peter Daszak speaks with The Scientist about how pathogens like 2019-nCoV jump species, and how to head off the next pandemic.

This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.

Researchers are trying to figure out where it came from, whether it’s evolving, and just how big a threat it will be.

While the findings contradict previous studies that have linked human herpesvirus 6 to the neurodegenerative disease, they do not eliminate the possibility of a relationship.

The number of cases spikes as the World Health Organization plans an emergency meeting on containing the epidemic.

A video chronicles the course of disease research and prompts questions about where scientists may focus their studies in the future.

The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.

The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.

Scientists release a draft genome of the virus that has been identified in 41 patients.

With millions of pigs killed due to a major outbreak of African swine fever virus in Asia, researchers have intensified efforts to find a vaccine quickly.

It’s now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process.

African swine fever virus has left the continent on three occasions, causing outbreaks in Europe, the Americas, and most recently, East Asia.

An accumulation of T cells and astrocytes in postmortem brain tissue hints at possible autoimmune origins for many cases of autism.

A tool for identifying jumping gene insertions in DNA sequencing data turns up possible explanations for four patients’ rare developmental disorders.