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image: Gene Expression Overlaps Among Psychiatric Disorders

Gene Expression Overlaps Among Psychiatric Disorders

By Ashley P. Taylor | February 8, 2018

Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression. 

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Researchers develop a new technique to selectively activate neurons deep in the rodent brain, taking a step toward noninvasive brain stimulation for neurological disorders.

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The compound, BCI-838, is already in human clinical trials as a possible treatment for depression.

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image: “Retired” Mice Find New Life as Top Models for Autism

“Retired” Mice Find New Life as Top Models for Autism

By Jessica Wright | January 29, 2018

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.

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image: Learning Opens the Genome

Learning Opens the Genome

By Ruth Williams | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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image: Rising Temperatures and the Elimination of Male Turtles

Rising Temperatures and the Elimination of Male Turtles

By Ruth Williams | January 10, 2018

The near-complete feminization of northern Great Barrier Reef sea turtles has been blamed on climate change.

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image: Scientists Continue to Use Outdated Methods

Scientists Continue to Use Outdated Methods

By Catherine Offord | January 9, 2018

The use of underperforming computational tools is a major offender in science’s reproducibility crisis—and there’s growing momentum to avoid it.

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Researchers identify patterns of neural activity ranging from a few days to four weeks in individuals with epilepsy.

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image: Primary Cilia in Neurons Linked to Obesity

Primary Cilia in Neurons Linked to Obesity

By Abby Olena | January 8, 2018

Three studies—one of mice and two of human genetics—describe the role of two proteins, adenylyl cyclase and melanocortin 4 receptor, in the development of obesity and diabetes. 

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The genome of an infant who lived in Alaska thousands of years ago represents a previously unknown group of humans called Ancient Beringians, who share a common lineage with other Native Americans. 

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