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image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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Researchers develop a new technique to selectively activate neurons deep in the rodent brain, taking a step toward noninvasive brain stimulation for neurological disorders.

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The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.

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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By Shawna Williams | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By Abby Olena | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By Abby Olena | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 

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image: New Resource Ranks Chemical Probes for Human Proteins

New Resource Ranks Chemical Probes for Human Proteins

By Abby Olena | December 14, 2017

With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Corals’ pH Sensor Identified

Corals’ pH Sensor Identified

By Ashley P. Taylor | November 1, 2017

Soluble adenylyl cyclase measures and responds to pH changes in coral cells, but whether it can help the animals withstand ocean acidification is not yet known.

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image: Opinion: How to Define Cell Type

Opinion: How to Define Cell Type

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.

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