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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 

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image: New Resource Ranks Chemical Probes for Human Proteins

New Resource Ranks Chemical Probes for Human Proteins

By | December 14, 2017

With many probes being seriously flawed, Probe Miner helps researchers find those that are most specific and effective for manipulating their chosen proteins.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Corals’ pH Sensor Identified

Corals’ pH Sensor Identified

By | November 1, 2017

Soluble adenylyl cyclase measures and responds to pH changes in coral cells, but whether it can help the animals withstand ocean acidification is not yet known.

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image: Opinion: How to Define Cell Type

Opinion: How to Define Cell Type

By , , and | November 1, 2017

Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: The Weird Growth Strategy of Earth’s First Trees

The Weird Growth Strategy of Earth’s First Trees

By | October 24, 2017

Ancient fossils reveal how woodless trees got so big: by continuously ripping apart their xylem and knitting it back together.

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Chemistry Nobel goes to Jacques Dubochet, Joachim Frank, and Richard Henderson. 

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