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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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image: The Biggest DNA Origami Structures Yet

The Biggest DNA Origami Structures Yet

By | December 6, 2017

Three new strategies for using DNA to generate large, self-assembling shapes create everything from a nanoscale teddy bear to a nanoscale Mona Lisa.

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image: The Rising Research Profile of 23andMe

The Rising Research Profile of 23andMe

By | December 1, 2017

An exploration of the genetics of earlobe attachment is just the latest collaborative research project to come out of the personal genetic testing company.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Six-Letter DNA Alphabet Produces Proteins in Cells

Six-Letter DNA Alphabet Produces Proteins in Cells

By | November 29, 2017

Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Hormone Loss Prevents Obesity and Diabetes in Mice

Hormone Loss Prevents Obesity and Diabetes in Mice

By | November 6, 2017

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

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image: The Genetic Strategies of Dealing with High Altitude

The Genetic Strategies of Dealing with High Altitude

By | November 2, 2017

Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.

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image: Corals’ pH Sensor Identified

Corals’ pH Sensor Identified

By | November 1, 2017

Soluble adenylyl cyclase measures and responds to pH changes in coral cells, but whether it can help the animals withstand ocean acidification is not yet known.

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image: Opinion: How to Define Cell Type

Opinion: How to Define Cell Type

By , , and | November 1, 2017

Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.

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