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image: Immune Checkpoint Found Lacking in Type 1 Diabetes

Immune Checkpoint Found Lacking in Type 1 Diabetes

By | November 15, 2017

Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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image: Child Receives Transgenic Skin Over Most of His Body

Child Receives Transgenic Skin Over Most of His Body

By | November 8, 2017

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.

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image: Hormone Loss Prevents Obesity and Diabetes in Mice

Hormone Loss Prevents Obesity and Diabetes in Mice

By | November 6, 2017

Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.

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image: The Genetic Strategies of Dealing with High Altitude

The Genetic Strategies of Dealing with High Altitude

By | November 2, 2017

Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.

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image: Opinion: How to Define Cell Type

Opinion: How to Define Cell Type

By , , and | November 1, 2017

Advances in single-cell technologies have revealed vast differences between cells once thought to be in the same category, calling into question how we define cell type in the first place.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: RNA Editing Possible with CRISPR-Cas13

RNA Editing Possible with CRISPR-Cas13

By | October 25, 2017

Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells.

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image: Genetic Risk Factors for Breast Cancer Identified

Genetic Risk Factors for Breast Cancer Identified

By | October 23, 2017

Researchers identify 72 novel genetic variants associated with breast cancer risk.

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image: Germany Sees Drastic Decrease in Insects

Germany Sees Drastic Decrease in Insects

By | October 18, 2017

A 27-year-long study finds insect biomass has declined by about 75 percent. 

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  3. Immune Checkpoint Found Lacking in Type 1 Diabetes
  4. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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