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image: Gene Expression Overlaps Among Psychiatric Disorders

Gene Expression Overlaps Among Psychiatric Disorders

By Ashley P. Taylor | February 8, 2018

Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression. 

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Researchers develop a new technique to selectively activate neurons deep in the rodent brain, taking a step toward noninvasive brain stimulation for neurological disorders.

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image: Bacteriophages Plentiful in Women’s Bladders

Bacteriophages Plentiful in Women’s Bladders

By Abby Olena | February 2, 2018

In one of the first looks at the urinary virome, researchers find hundreds of viruses, most of which have never been sequenced before. 

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The compound, BCI-838, is already in human clinical trials as a possible treatment for depression.

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image: “Retired” Mice Find New Life as Top Models for Autism

“Retired” Mice Find New Life as Top Models for Autism

By Jessica Wright | January 29, 2018

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.

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The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.

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image: How Gaining and Losing Weight Affects the Body

How Gaining and Losing Weight Affects the Body

By Abby Olena | January 17, 2018

Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

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image: Learning Opens the Genome

Learning Opens the Genome

By Ruth Williams | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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Scientists are beginning to unravel the ways in which we develop a healthy relationship with the bugs in our bodies.

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image: Scientists Continue to Use Outdated Methods

Scientists Continue to Use Outdated Methods

By Catherine Offord | January 9, 2018

The use of underperforming computational tools is a major offender in science’s reproducibility crisis—and there’s growing momentum to avoid it.

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