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image: Monitoring Mutations with Microfluidics

Monitoring Mutations with Microfluidics

By Ruth Williams | March 15, 2018

A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  


The finding suggests corvids may have an innate sense of number.


Host slugs given Prozac to increase their serotonin levels no longer avoid parasitic nematodes, the same behavior seen in infected slugs.


Including microbiome composition in predictions of whether a person is obese can significantly improve their accuracy, according to an analysis.


image: Gene Expression Overlaps Among Psychiatric Disorders

Gene Expression Overlaps Among Psychiatric Disorders

By Ashley P. Taylor | February 8, 2018

Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression. 


Researchers develop a new technique to selectively activate neurons deep in the rodent brain, taking a step toward noninvasive brain stimulation for neurological disorders.


The compound, BCI-838, is already in human clinical trials as a possible treatment for depression.


image: “Retired” Mice Find New Life as Top Models for Autism

“Retired” Mice Find New Life as Top Models for Autism

By Jessica Wright | January 29, 2018

After years of obscurity, strains of mice with mutations in particular genes are thrust to the fore of autism research.


image: Learning Opens the Genome

Learning Opens the Genome

By Ruth Williams | January 17, 2018

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

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image: Opinion: Label Drugs That Are Tested on Animals

Opinion: Label Drugs That Are Tested on Animals

By Shaun Khoo | January 16, 2018

Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.

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