The 10-micrometer-long flagellate cell might have a big story to tell about the evolution of eukaryotes.
May 27, 2002|
Post-translational regulation of p53 regulates its activity and tumor suppressor functions. In an Advanced Online Publication in Nature Genetics, Dmitry Bulavin and colleagues from the National Institutes of Health describe how oncogenic Ras regulates p53 phosphorylation (Nat Genet 2002, DOI:10.1038/ng894).Bulavin et al. used antibodies specific for different modified forms of p53 and showed that oncogenic Ras induced p53, accumulation and phosphorylation of two specific serine residues that are