Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.
January 7, 2002|
Uncoupling proteins (UCPs) are molecules that usually generate heat in the mitochondria of brown adipose tissue, but their function in other tissues remains unclear. In 3 January Nature, Karim Echtay and colleagues from the Medical Research Council's Dunn Human Nutrition Unit, Cambridge, UK, show that UCPs may have a role in decreasing reactive oxygen species concentrations inside mitochondria.Echtay et al. observed that superoxide increases mitochondrial proton conductance through effects on UC