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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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image: Behavior Circuits Mapped in Whole Fruit Fly Brain

Behavior Circuits Mapped in Whole Fruit Fly Brain

By | July 13, 2017

Using machine learning, researchers have created extensive maps of the neuronal circuits associated with social and locomotion behaviors in the fruit fly. 

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image: Electrical Stimulation Steers Neural Stem Cells

Electrical Stimulation Steers Neural Stem Cells

By | July 3, 2017

Current can guide implanted cells away from rats’ noses toward a region deep in their brains.

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image: Transgenic Mouse Illuminates Melanoma Metastasis

Transgenic Mouse Illuminates Melanoma Metastasis

By | June 28, 2017

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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image: How Roundworms Sleep

How Roundworms Sleep

By | June 22, 2017

When Caenorhabditis elegans surrenders to slumber, the majority of its neurons fall silent.

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image: Gut Feeling

Gut Feeling

By | June 22, 2017

Sensory cells of the mouse intestine let the brain know if certain compounds are present by speaking directly to gut neurons via serotonin.

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